A DdeI PCR-RFLP detecting genetic variation of goat POU1F1 gene
نویسندگان
چکیده
منابع مشابه
DdeI Polymorphism in Coding Region of Goat POU1F1 Gene and Its Association with Production Traits
POU1F1 is a positive regulator for GH, PRL and TSHβ and its mutations associate with production traits in ruminant animals. We described a DdeI PCR-RFLP method for detecting a silent allele in the goat POU1F1 gene: TCT (241Ser)>TCG (241Ser). Frequencies of D1 allele varied from 0.600 to 1.000 in Chinese 801 goats. Significant associations of DdeI polymorphism with production traits were found i...
متن کاملAnalysis of POU1F1 gene DdeI polymorphism in Chinese goats.
As a member of the POU-domain family, the POU1F1 is a positive regulator for growth hormone, prolactin and thyroid-stimulating hormone b, by binding to target DNA promoters as a dimer in mammals. This study described the polymorphisms at the goat POU1F1-DdeI locus and analyzed the distribution of alleles in 15 indigenous Chinese goat breeds. The PCR-RFLP analysis showed a predominance of the D1...
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ژورنال
عنوان ژورنال: Canadian Journal of Animal Science
سال: 2007
ISSN: 0008-3984,1918-1825
DOI: 10.4141/a06-068